Publications

Marrone GF, Le Rouzic V, Varadi A, Xu J, Rajadhyaksha AM, Majumdar S, Pan Y-X, Pasternak GW.  2017.  Genetic dissociation of morphine analgesia from hyperalgesia in mice.. Psychopharmacology (Berl). 234(12):1891-1900.

Kelly NH, Rajadhyaksha AD, Wright TM, Maher SA, Westrich GH.  2010.  High stress conditions do not increase wear of thin highly crosslinked UHMWPE.. Clin Orthop Relat Res. 468(2):418-23.

Leveque JC, Macías W, Rajadhyaksha A, Carlson RR, Barczak A, Kang S, Li XM, Coyle JT, Huganir RL, Heckers S et al..  2000.  Intracellular modulation of NMDA receptor function by antipsychotic drugs.. J Neurosci. 20(11):4011-20.

Moeller S, Lau NM, Green PHR, Hellberg D, Higgins JJ, Rajadhyaksha AM, Alaedini A.  2013.  Lack of association between autism and anti-GM1 ganglioside antibody.. Neurology. 81(18):1640-1.

Akuffo AA, Alontaga AY, Metcalf R, Beatty MS, Becker A, McDaniel JM, Hesterberg RS, Goodheart WE, Gunawan S, Ayaz M et al..  2018.  Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon.. J Biol Chem. 293(16):6187-6200.

Ambrose C, Lowman H, Rajadhyaksha A, Blasquez V, Bina M.  1990.  Location of nucleosomes in simian virus 40 chromatin.. J Mol Biol. 214(4):875-84.

Ambrose C, Rajadhyaksha A, Lowman H, Bina M.  1989.  Locations of nucleosomes on the regulatory region of simian virus 40 chromatin.. J Mol Biol. 210(2):255-63.

Eaton ME, Macías W, Youngs RM, Rajadhyaksha A, Dudman JT, Konradi C.  2004.  L-type Ca2+ channel blockers promote Ca2+ accumulation when dopamine receptors are activated in striatal neurons.. Brain Res Mol Brain Res. 131(1-2):65-72.

Rajadhyaksha A, Barczak A, Macías W, Leveque JC, Lewis SE, Konradi C.  1999.  L-Type Ca(2+) channels are essential for glutamate-mediated CREB phosphorylation and c-fos gene expression in striatal neurons.. J Neurosci. 19(15):6348-59.

Kabir ZD, Lee AS, Rajadhyaksha AM.  2016.  L-type Ca(2+) channels in mood, cognition and addiction: integrating human and rodent studies with a focus on behavioural endophenotypes.. J Physiol. 594(20):5823-5837.

Rajadhyaksha A, Husson I, Satpute SS, Küppenbender KD, Ren JQ, Guerriero RM, Standaert DG, Kosofsky BE.  2004.  L-type Ca2+ channels mediate adaptation of extracellular signal-regulated kinase 1/2 phosphorylation in the ventral tegmental area after chronic amphetamine treatment.. J Neurosci. 24(34):7464-76.

Addy NA, Nunes EJ, Hughley SM, Small KM, Baracz SJ, Haight JL, Rajadhyaksha AM.  2018.  The L-type calcium channel blocker, isradipine, attenuates cue-induced cocaine-seeking by enhancing dopaminergic activity in the ventral tegmental area to nucleus accumbens pathway.. Neuropsychopharmacology.

Lau NM, Green PHR, Taylor AK, Hellberg D, Ajamian M, Tan CZ, Kosofsky BE, Higgins JJ, Rajadhyaksha AM, Alaedini A.  2013.  Markers of Celiac Disease and Gluten Sensitivity in Children with Autism.. PLoS One. 8(6):e66155.

Rajadhyaksha A, Leveque J, Macías W, Barczak A, Konradi C.  1998.  Molecular components of striatal plasticity: the various routes of cyclic AMP pathways.. Dev Neurosci. 20(2-3):204-15.

Giordano TP, Tropea TF, Satpute SS, Sinnegger-Brauns MJ, Striessnig J, Kosofsky BE, Rajadhyaksha AM.  2010.  Molecular switch from L-type Ca v 1.3 to Ca v 1.2 Ca2+ channel signaling underlies long-term psychostimulant-induced behavioral and molecular plasticity.. J Neurosci. 30(50):17051-62.

Rajadhyaksha AM, Elemento O, Puffenberger EG, Schierberl KC, Xiang JZ, Putorti ML, Berciano J, Poulin C, Brais B, Michaelides M et al..  2010.  Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa.. Am J Hum Genet. 87(5):643-54.

Lee AS, De Jesús-Cortés H, Kabir ZD, Knobbe W, Orr M, Burgdorf C, Huntington P, McDaniel L, Britt JK, Hoffmann F et al..  2016.  The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons.. eNeuro. 3(2)

Tesmer VM, Rajadhyaksha A, Babin J, Bina M.  1993.  NF-IL6-mediated transcriptional activation of the long terminal repeat of the human immunodeficiency virus type 1.. Proc Natl Acad Sci U S A. 90(15):7298-302.

Covington HE, Tropea TF, Rajadhyaksha AM, Kosofsky BE, Miczek KA.  2008.  NMDA receptors in the rat VTA: a critical site for social stress to intensify cocaine taking.. Psychopharmacology (Berl). 197(2):203-16.

Macías W, Carlson R, Rajadhyaksha A, Barczak A, Konradi C.  2001.  Potassium chloride depolarization mediates CREB phosphorylation in striatal neurons in an NMDA receptor-dependent manner.. Brain Res. 890(2):222-32.

Ren J-Q, Jiang Y, Wang Z, McCarthy D, Rajadhyaksha AM, Tropea TF, Kosofsky BE, Bhide PG.  2011.  Prenatal L-DOPA exposure produces lasting changes in brain dopamine content, cocaine-induced dopamine release and cocaine conditioned place preference.. Neuropharmacology. 60(2-3):295-302.

Rajadhyaksha AM, Kosofsky BE.  2005.  Psychostimulants, L-type calcium channels, kinases, and phosphatases.. Neuroscientist. 11(5):494-502.

Bavley CC, Rice RC, Fischer DK, Fakira AK, Byrne M, Kosovsky M, Rizzo BK, Del Prete D, Alaedini A, Morón JA et al..  2018.  Rescue of Learning and Memory Deficits in the Human Nonsyndromic Intellectual Disability Cereblon Knock-Out Mouse Model by Targeting the AMP-Activated Protein Kinase-mTORC1 Translational Pathway.. J Neurosci. 38(11):2780-2795.

Lee AS, Gonzales KL, Lee A, Moosmang S, Hofmann F, Pieper AA, Rajadhyaksha AM.  2012.  Selective genetic deletion of cacna1c in the mouse prefrontal cortex.. Mol Psychiatry. 17(11):1051.

Mende M, Fletcher EV, Belluardo JL, Pierce JP, Bommareddy PK, Weinrich JA, Kabir ZD, Schierberl KC, Pagiazitis JG, Mendelsohn AI et al..  2016.  Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord.. Neuron. 90(6):1189-202.