Publications

Kabir ZD, Lourenco F, Byrne ME, Katzman A, Lee F, Rajadhyaksha AM, Kosofsky BE.  2012.  Brain-derived neurotrophic factor genotype impacts the prenatal cocaine-induced mouse phenotype.. Dev Neurosci. 34(2-3):184-97.

Kabir ZD, Lee AS, Rajadhyaksha AM.  2016.  L-type Ca(2+) channels in mood, cognition and addiction: integrating human and rodent studies with a focus on behavioural endophenotypes.. J Physiol. 594(20):5823-5837.

Kabir ZD, Martinez-Rivera A, Rajadhyaksha AM.  2017.  From Gene to Behavior: L-Type Calcium Channel Mechanisms Underlying Neuropsychiatric Symptoms.. Neurotherapeutics. 14(3):588-613.

Kelly NH, Rajadhyaksha AD, Wright TM, Maher SA, Westrich GH.  2010.  High stress conditions do not increase wear of thin highly crosslinked UHMWPE.. Clin Orthop Relat Res. 468(2):418-23.

Lau NM, Green PHR, Taylor AK, Hellberg D, Ajamian M, Tan CZ, Kosofsky BE, Higgins JJ, Rajadhyaksha AM, Alaedini A.  2013.  Markers of Celiac Disease and Gluten Sensitivity in Children with Autism.. PLoS One. 8(6):e66155.

Lee AS, Ra S, Rajadhyaksha AM, Britt JK, De Jesus-Cortes H, Gonzales KL, Lee A, Moosmang S, Hofmann F, Pieper AA et al..  2012.  Forebrain elimination of cacna1c mediates anxiety-like behavior in mice.. Mol Psychiatry. 17(11):1054-5.

Lee AS, Gonzales KL, Lee A, Moosmang S, Hofmann F, Pieper AA, Rajadhyaksha AM.  2012.  Selective genetic deletion of cacna1c in the mouse prefrontal cortex.. Mol Psychiatry. 17(11):1051.

Lee AS, De Jesús-Cortés H, Kabir ZD, Knobbe W, Orr M, Burgdorf C, Huntington P, McDaniel L, Britt JK, Hoffmann F et al..  2016.  The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons.. eNeuro. 3(2)

Leveque JC, Macías W, Rajadhyaksha A, Carlson RR, Barczak A, Kang S, Li XM, Coyle JT, Huganir RL, Heckers S et al..  2000.  Intracellular modulation of NMDA receptor function by antipsychotic drugs.. J Neurosci. 20(11):4011-20.

Liu Y, Harding M, Pittman A, Dore J, Striessnig J, Rajadhyaksha A, Chen X.  2014.  Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.. J Neurophysiol. 112(5):1119-30.

Macías W, Carlson R, Rajadhyaksha A, Barczak A, Konradi C.  2001.  Potassium chloride depolarization mediates CREB phosphorylation in striatal neurons in an NMDA receptor-dependent manner.. Brain Res. 890(2):222-32.

Marrone GF, Le Rouzic V, Varadi A, Xu J, Rajadhyaksha AM, Majumdar S, Pan Y-X, Pasternak GW.  2017.  Genetic dissociation of morphine analgesia from hyperalgesia in mice.. Psychopharmacology (Berl). 234(12):1891-1900.

Martínez-Rivera A, Hao J, Tropea TF, Giordano TP, Kosovsky M, Rice RC, Lee A, Huganir RL, Striessnig J, Addy NA et al..  2017.  Enhancing VTA Cav1.3 L-type Ca(2+) channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens.. Mol Psychiatry.

Mende M, Fletcher EV, Belluardo JL, Pierce JP, Bommareddy PK, Weinrich JA, Kabir ZD, Schierberl KC, Pagiazitis JG, Mendelsohn AI et al..  2016.  Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord.. Neuron. 90(6):1189-202.

Moeller S, Lau NM, Green PHR, Hellberg D, Higgins JJ, Rajadhyaksha AM, Alaedini A.  2013.  Lack of association between autism and anti-GM1 ganglioside antibody.. Neurology. 81(18):1640-1.

Na ES, De Jesús-Cortés H, Martinez-Rivera A, Kabir ZD, Wang J, Ramesh V, Onder Y, Rajadhyaksha AM, Monteggia LM, Pieper AA.  2017.  D-cycloserine improves synaptic transmission in an animal model of Rett syndrome.. PLoS One. 12(8):e0183026.

Rajadhyaksha A, Husson I, Satpute SS, Küppenbender KD, Ren JQ, Guerriero RM, Standaert DG, Kosofsky BE.  2004.  L-type Ca2+ channels mediate adaptation of extracellular signal-regulated kinase 1/2 phosphorylation in the ventral tegmental area after chronic amphetamine treatment.. J Neurosci. 24(34):7464-76.

Rajadhyaksha AM, Ra S, Kishinevsky S, Lee AS, Romanienko P, DuBoff M, Yang C, Zupan B, Byrne M, Daruwalla ZR et al..  2012.  Behavioral characterization of cereblon forebrain-specific conditional null mice: a model for human non-syndromic intellectual disability.. Behav Brain Res. 226(2):428-34.

Rajadhyaksha A, Rivière M, Van Vooren P, Szpirer J, Szpirer C, Babin J, Bina M.  1998.  Assignment of AR1, transcription factor 20 (TCF20), to human chromosome 22q13.3 with somatic cell hybrids and in situ hybridization.. Cytogenet Cell Genet. 81(3-4):176-7.

Rajadhyaksha AM, Elemento O, Puffenberger EG, Schierberl KC, Xiang JZ, Putorti ML, Berciano J, Poulin C, Brais B, Michaelides M et al..  2010.  Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa.. Am J Hum Genet. 87(5):643-54.

Rajadhyaksha A, Leveque J, Macías W, Barczak A, Konradi C.  1998.  Molecular components of striatal plasticity: the various routes of cyclic AMP pathways.. Dev Neurosci. 20(2-3):204-15.

Rajadhyaksha AM, Kosofsky BE.  2005.  Psychostimulants, L-type calcium channels, kinases, and phosphatases.. Neuroscientist. 11(5):494-502.

Rajadhyaksha A, Barczak A, Macías W, Leveque JC, Lewis SE, Konradi C.  1999.  L-Type Ca(2+) channels are essential for glutamate-mediated CREB phosphorylation and c-fos gene expression in striatal neurons.. J Neurosci. 19(15):6348-59.

Ren J-Q, Jiang Y, Wang Z, McCarthy D, Rajadhyaksha AM, Tropea TF, Kosofsky BE, Bhide PG.  2011.  Prenatal L-DOPA exposure produces lasting changes in brain dopamine content, cocaine-induced dopamine release and cocaine conditioned place preference.. Neuropharmacology. 60(2-3):295-302.

Schierberl KC, Rajadhyaksha AM.  2013.  Stereotaxic microinjection of viral vectors expressing Cre recombinase to study the role of target genes in cocaine conditioned place preference.. J Vis Exp. (77)