Publications

Akuffo AA, Alontaga AY, Metcalf R, Beatty MS, Becker A, McDaniel JM, Hesterberg RS, Goodheart WE, Gunawan S, Ayaz M et al..  2018.  Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon.. J Biol Chem. 293(16):6187-6200.

Moeller S, Lau NM, Green PHR, Hellberg D, Higgins JJ, Rajadhyaksha AM, Alaedini A.  2013.  Lack of association between autism and anti-GM1 ganglioside antibody.. Neurology. 81(18):1640-1.

Leveque JC, Macías W, Rajadhyaksha A, Carlson RR, Barczak A, Kang S, Li XM, Coyle JT, Huganir RL, Heckers S et al..  2000.  Intracellular modulation of NMDA receptor function by antipsychotic drugs.. J Neurosci. 20(11):4011-20.

Kelly NH, Rajadhyaksha AD, Wright TM, Maher SA, Westrich GH.  2010.  High stress conditions do not increase wear of thin highly crosslinked UHMWPE.. Clin Orthop Relat Res. 468(2):418-23.

Marrone GF, Le Rouzic V, Varadi A, Xu J, Rajadhyaksha AM, Majumdar S, Pan Y-X, Pasternak GW.  2017.  Genetic dissociation of morphine analgesia from hyperalgesia in mice.. Psychopharmacology (Berl). 234(12):1891-1900.

Kabir ZD, Martinez-Rivera A, Rajadhyaksha AM.  2017.  From Gene to Behavior: L-Type Calcium Channel Mechanisms Underlying Neuropsychiatric Symptoms.. Neurotherapeutics. 14(3):588-613.

Lee AS, Ra S, Rajadhyaksha AM, Britt JK, De Jesus-Cortes H, Gonzales KL, Lee A, Moosmang S, Hofmann F, Pieper AA et al..  2012.  Forebrain elimination of cacna1c mediates anxiety-like behavior in mice.. Mol Psychiatry. 17(11):1054-5.

Burgdorf CE, Schierberl KC, Lee AS, Fischer DK, Van Kempen TA, Mudragel V, Huganir RL, Milner TA, Glass MJ, Rajadhyaksha AM.  2017.  Extinction of contextual cocaine memories requires Cav1.2 within D1R-expressing cells and recruits hippocampal Cav1.2-dependent signaling mechanisms. Journal Of Neuroscience.

Martínez-Rivera A, Hao J, Tropea TF, Giordano TP, Kosovsky M, Rice RC, Lee A, Huganir RL, Striessnig J, Addy NA et al..  2017.  Enhancing VTA Cav1.3 L-type Ca(2+) channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens.. Mol Psychiatry.

Tropea TF, Kosofsky BE, Rajadhyaksha AM.  2008.  Enhanced CREB and DARPP-32 phosphorylation in the nucleus accumbens and CREB, ERK, and GluR1 phosphorylation in the dorsal hippocampus is associated with cocaine-conditioned place preference behavior.. J Neurochem. 106(4):1780-90.

Inan M, Zhao M, Manuszak M, Karakaya C, Rajadhyaksha AM, Pickel VM, Schwartz TH, Goldstein PA, Manfredi G.  2016.  Energy deficit in parvalbumin neurons leads to circuit dysfunction, impaired sensory gating and social disability.. Neurobiol Dis. 93:35-46.

Higgins JJ, Hao J, Kosofsky BE, Rajadhyaksha AM.  2008.  Dysregulation of large-conductance Ca2+-activated K+ channel expression in nonsyndromal mental retardation due to a cereblon p.R419X mutation.. Neurogenetics. 9(3):219-23.

Dudman JT, Eaton ME, Rajadhyaksha A, Macías W, Taher M, Barczak A, Kameyama K, Huganir R, Konradi C.  2003.  Dopamine D1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor at Ser897-NR1.. J Neurochem. 87(4):922-34.

Bogulavsky JJ, Gregus AM, Kim PT-H, Costa ACS, Rajadhyaksha AM, Inturrisi CE.  2009.  Deletion of the glutamate receptor 5 subunit of kainate receptors affects the development of morphine tolerance.. J Pharmacol Exp Ther. 328(2):579-87.

Gregus AM, Tropea TF, Wang Y, Hauck SCR, Costa ACS, Rajadhyaksha AM, Inturrisi CE.  2010.  Deletion of the GluR5 subunit of kainate receptors affects cocaine sensitivity and preference.. Neurosci Lett. 468(3):186-9.

Na ES, De Jesús-Cortés H, Martinez-Rivera A, Kabir ZD, Wang J, Ramesh V, Onder Y, Rajadhyaksha AM, Monteggia LM, Pieper AA.  2017.  D-cycloserine improves synaptic transmission in an animal model of Rett syndrome.. PLoS One. 12(8):e0183026.

Schierberl K, Hao J, Tropea TF, Ra S, Giordano TP, Xu Q, Garraway SM, Hofmann F, Moosmang S, Striessnig J et al..  2011.  Cav1.2 L-type Ca²⁺ channels mediate cocaine-induced GluA1 trafficking in the nucleus accumbens, a long-term adaptation dependent on ventral tegmental area Ca(v)1.3 channels.. J Neurosci. 31(38):13562-75.

Bavley CC, Fischer DK, Rizzo BK, Rajadhyaksha AM.  2017.  Cav1.2 channels mediate persistent chronic stress-induced behavioral deficits that are associated with prefrontal cortex activation of the p25/Cdk5-glucocorticoid receptor pathway.. Neurobiol Stress. 7:27-37.

Liu Y, Harding M, Pittman A, Dore J, Striessnig J, Rajadhyaksha A, Chen X.  2014.  Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.. J Neurophysiol. 112(5):1119-30.

Schierberl K, Giordano T, Satpute S, Hao J, Kaur G, Hofmann F, Moosmang S, Striessnig J, Rajadhyaksha A.  2012.  Cav 1.3 L-type Ca ( 2+) channels mediate long-term adaptation in dopamine D2L-mediated GluA1 trafficking in the dorsal striatum following cocaine exposure.. Channels (Austin). 6(1):11-7.

De Jesús-Cortés H, Rajadhyaksha AM, Pieper AA.  2016.  Cacna1c: Protecting young hippocampal neurons in the adult brain.. Neurogenesis (Austin). 3(1):e1231160.

Kabir ZD, Lee AS, Burgdorf CE, Fischer DK, Rajadhyaksha AM, Mok E, Rizzo B, Rice RC, Singh K, Ota KT et al..  2017.  Cacna1c in the Prefrontal Cortex Regulates Depression-Related Behaviors via REDD1.. Neuropsychopharmacology.

Kabir ZD, Lourenco F, Byrne ME, Katzman A, Lee F, Rajadhyaksha AM, Kosofsky BE.  2012.  Brain-derived neurotrophic factor genotype impacts the prenatal cocaine-induced mouse phenotype.. Dev Neurosci. 34(2-3):184-97.

Rajadhyaksha AM, Ra S, Kishinevsky S, Lee AS, Romanienko P, DuBoff M, Yang C, Zupan B, Byrne M, Daruwalla ZR et al..  2012.  Behavioral characterization of cereblon forebrain-specific conditional null mice: a model for human non-syndromic intellectual disability.. Behav Brain Res. 226(2):428-34.

Ajamian M, Rajadhyaksha AM, Alaedini A.  2013.  Autism and Lyme disease--reply.. JAMA. 310(8):857.